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Stem cells and exosomes may protect neuron function by many mechanisms including releasing neurotrophic growth factors, regulating glial cell activity, enhancing BDNF activity, shutting off neuroinflammatory signals, controling cell turnover and cell death, downregulating formation of plaque, gliosis, and scar, and upregulating microRNA expression signals for neural repair (13) (14) (15) (16) (17) (18)

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Exercise increases IGF-1 and angiogenesis